Oxidative and nitrosative stress in brain mitochondria of diabetic rats

Effect of Oleuropein Extract from Olive on Brain Oxidative Stress in Ovariectomized Diabetic Rats

Background and objectives: Increased oxidative stress and altered antioxidant levels play an essential role in the pathogenesis of diabetes mellitus. Menopause is associated with increased food intake, weight gain, metabolic disorders, and increased level of inflammatory and oxidative stress factors. This study evaluated effects of oleuropein extract on brain tissue and serum oxidative status i...

Enalapril attenuates oxidative stress in diabetic rats.

Oxidative stress is involved in both the pathogenesis and complications of diabetes. ACE inhibitors can slow the progression of cardiac and renal impairments related to diabetes. The effect of enalapril treatment on oxidative stress and tissue injury was studied in hearts, kidneys, and livers from streptozotocin-induced diabetic rats. Twenty-four rats were divided into the following groups: str...

The efficiency of oxidative phosphorylation in mitochondria from diabetic rats.

Considerable evidence has accumulated which indicates that insulin plays an important rBle in phosphate metabolism (1, 2). A number of workers have postulated that insulin has as its primary function the regulation of the efficiency of oxidative phosphorylation. In attempts to test this hypothesis, Goranson and Erulkar (3) observed that tissues from alloxan-diabetic rats appear to fix phosphate...

depleted uranium induces disruption of energy hemostasis and oxidative stress in isolated rat brain mitochondria

Evaluation of Δ9-tetrahydrocannabinol metabolites and oxidative stress in type 2 diabetic rats

Objective(s): The object of the study is to examine the effects of Δ9-tetrahydrocannabinol (THC) against oxidative stress in the blood and excretion of THC metabolites in urine of type 2 diabetic rats. Materials and Methods: The control (n=8), THC control (n=6), diabetes (n=8) and diabetes + THC (n=7) groups were created. Type 2 diabetes was induced by nicotinamide (NA, 85 mg/kg) + streptozotoc...